Downregulation of Cyclophilin A by siRNA diminishes non-small cell lung cancer cell growth and metastasis via the regulation of matrix metallopeptidase 9

Abstract Background Cyclophilin A (CypA) is a cytosolic protein possessing peptidyl-prolyl isomerase activity that was recently reported to be overexpressed in several cancers.Here, we explored the biology and molecular mechanism of CypA in non-small cell lung cancer (NSCLC).Methods The expression of CypA in human NSCLC cell lines was detected by r

read more



Structural Health Monitoring (SHM) of Machine Using a Combination of Non-Destructive Testing for Heavy Manufacturing Industry

Markets are affected by assorted consumer requirements, which insist on superior quality, shorter delivery time, better customer support, and lower prices.Simultaneously, product life cycles are becoming shorter.Success relies on having either a cost-benefit or a value benefit, or, both in any competitive context.Therefore, non-destructive techniqu

read more